Sulfosuccinimidyl oleate sodium
CAS No. 1212012-37-7
Sulfosuccinimidyl oleate sodium ( Sulfo-N-succinimidyl oleate sodium )
Catalog No. M26470 CAS No. 1212012-37-7
Sulfosuccinimidyl oleate sodium is a long-chain fatty acid that inhibits the transport of fatty acids to cells. Sulfosuccinimidyl oleate sodium is an effective, irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to CD36 receptors on the surface of microglia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 59 | Get Quote |
|
10MG | 107 | Get Quote |
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25MG | 177 | Get Quote |
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50MG | 284 | Get Quote |
|
100MG | 447 | Get Quote |
|
200MG | 574 | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameSulfosuccinimidyl oleate sodium
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NoteResearch use only, not for human use.
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Brief DescriptionSulfosuccinimidyl oleate sodium is a long-chain fatty acid that inhibits the transport of fatty acids to cells. Sulfosuccinimidyl oleate sodium is an effective, irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to CD36 receptors on the surface of microglia.
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DescriptionSulfosuccinimidyl oleate sodium is a long-chain fatty acid that inhibits the transport of fatty acids to cells. Sulfosuccinimidyl oleate sodium is an effective, irreversible inhibitor of mitochondrial respiratory chain. Sulfosuccinimidyl oleate sodium binds to CD36 receptors on the surface of microglia.(In Vitro):Sulfosuccinimidyl oleate (50 μM, 24 hours) co-treatment significantly reduces the LPS+IFNγ-induced expression of NOS2 and COX-2 in BV2 cells. Western blot analysis reveals a significant LPS/IFNγ-induced upregulation in the phosphorylated form of the p38, which is prevented by co-treatment with Sulfosuccinimidyl oleate (50 μM, 24 hours).(In Vivo):In male BALB/cABom mice with pMCAo model, Sulfosuccinimidyl oleate (50 mg/kg; administered once by single oral gavage) significantly reduces the cortical ischemic infarct size compared to vehicle-treated controls. In addition, Sulfosuccinimidyl oleate(50 mg/kg) is suitable to see a beneficial effect after stroke.
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SynonymsSulfo-N-succinimidyl oleate sodium
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PathwayOthers
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TargetOther Targets
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Recptorinflammation
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Research Area——
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Indication——
Chemical Information
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CAS Number1212012-37-7
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Formula Weight481.6
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Molecular FormulaC22H36NNaO7S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C(C1)C(N(OC(CCCCCCC/C=C\CCCCCCCC)=O)C1=O)=O)(O[Na])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kohno K, Ohashi E, et al. Anti-inflammatory effects of adenosine N1-oxide. J Inflamm (Lond). 2015 Jan 20;12(1):2.
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